منابع مشابه
Malignant melanoma of the conjunctiva.
BACKGROUND Conjunctival melanoma is a relatively rare ocular malignancy with substantial associated morbidity and mortality. METHODS More than 100 articles on conjunctival melanoma were reviewed, including most of the relevant recent publications cited in a current MEDLINE search. The author's experience with conjunctival melanomas is also incorporated in this review. RESULTS Recognition of...
متن کاملMetastatic malignant melanoma of the conjunctiva: a case report
BACKGROUND Malignant melanoma of the conjunctiva is an extremely rare non-cutaneous neoplasm with infrequent skeletal metastatic spread. CASE PRESENTATION We present the case of a 54 year old female Caucasian patient with osseous metastases originating from a malignant melanoma of her right conjunctiva. Metastatic deposits were identified in the left humeral diaphysis and left tibial metaphys...
متن کاملMalignant melanoma of the conjunctiva: a case report with examination of KIT and PDGFRA
Although many clinicopathological studies of malignant melanoma of the conjunctiva have been reported, there have been no studies of the expression and gene mutations of KIT and PDGFRA in melanoma of the conjunctiva. A 69-year-old Japanese woman consulted our hospital because of black mass (0.7 × 0.7 × 0.6 cm) in the conjunctiva. A biopsy was taken. The biopsy showed malignant epithelioid cells...
متن کاملCASE 4. A black eye: melanoma in situ of the conjunctiva.
A 77-year-old woman consulted an ophthalmologist because her left eye had “turned black” during the last 6 to 9 months. In addition, she felt that her eye was “sinking in the orbit.” Visual acuity was reduced to 20/30. The right eye was normal with 20/20 vision. The nasal, temporal, and especially, the upper conjunctiva (Fig 1A) of her left eye contained literally myriad dark brown pigment depo...
متن کاملLack of oncogenic GNAQ mutations in melanocytic lesions of the conjunctiva as compared to uveal melanoma.
PURPOSE Somatic mutations in codon 209 of the GNAQ gene are the first initiating events to be identified in uveal melanoma. The purpose of this study was to search for GNAQ209 mutations in conjunctival melanocytic lesions. METHODS Forty archival samples of conjunctival melanocytic lesions (conjunctival nevi, primary acquired melanosis, and conjunctival melanoma), 27 samples of uveal melanoma,...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1927
ISSN: 0035-9157
DOI: 10.1177/003591572702000758